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Sugarcane Genome Sequencing

Sugarcane cultivars derive from a recent interspecific hybrid obtained by crossing Saccharum officinarum and Saccharum spontaneum and represent relevant feedstock used worldwide for biofuel production.

The challenge in a sugarcane sequencing project is the size (10 Gb) and complexity of its genome structure that is highly polyploid and aneuploid with a complete set of homo(eo)logous genes predicted to range from 8 to 10 copies (alleles). Although sugarcane's monoploid genome is about 1 Gb, its highly polymorphic nature represent another significant challenge for obtaining a genuine assembled monoploid genome.

 

Vettore, A. L., da Silva, F. R., Kemper, E. L., Souza, G. M. et al. (2003). Analysis and functional annotation of an expressed sequence tag collection for the tropical crop sugarcane. Genome Res. 13, 2725-2735. 

Souza, G. M., Berges, H., Bocs, S. S., Casu, R., D, Berg A., Ferreira, J. E., Henry, R., Ming, R., Potier, B., Van Sluys, M. A., Vincentz, M., Paterson, A. H. The Sugarcane Genome Challenge: Strategies for Sequencing a Highly Complex Genome. (2011). Tropical Plant Biology 4, 145-156. DOI: 10.1007/s12042-011-9079-0

Paterson, A. H., Souza, G. M., Van-Sluys, M. A., Ming, R. and Angelique D’Hont. Structural genomics and genome sequencing in sugarcane. In: Sugarcane volume of “Genomics of Industrial Crop Plants”. Robert Henry (Org). in press.

Hoarau, J. Y.; Souza, G. M.; D'Hont, A.; Menossi, M.; Pinto, L.R.; Souza, A. P.; Grivet, L.; Menck, C. F. M.; Ulian, E. C.; Vincentz, M. (2007). Sugarcane, a tropical crop with a highly complex genome. In: J. F. Morot-Gaudry, P. Lea and J. F. Briat. (Org.). Functional Plant Genomics. Science Publishers.

Ferreira, S. S.; Nishiyama-Junior, M. Y.; Paterson, A. H.; Souza, G. M. (2013). Biofuel and energy crops: high-yield Saccharinae take center stage in the post-genomics era. http://glauciasouza.com/articles/Ferreira-et-al.pdf.

Visit http://sugarcanegenome.org .

About


Dr. Glaucia Souza holds a degree from the Biosciences Institute of University of São Paulo  (1988), PhD in Biochemistry at the Institute of Chemistry  (1993), post-doctorate in molecular genetics at La Jolla Cancer Research Foundation  (1994) and post-doctorate in molecular genetics at Baylor College of Medicine  (1996).

Post-doctoral position for two years at University of São Paulo, Brazil