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Transcription Factors and Regulatory Networks

We intend to implement the ChIP-Seq technology in sugarcane, to identify TF targets and gene promoters.

The results will have multiple direct consequences on breeding programs that frequently select for CREs and TF changes in search for genotypes better adapted to the environment and with increased agronomical performance.

We also participate in the development of the GRASSIUS database to establish sugarcane, rice, maize and sorghum regulatory networks.


Moraes, I., Yuan, Z. F., Liu, S., Souza, G. M., Garcia, B. A., Casas-Mollano, J. A. (2015). Analysis of Histones H3 and H4 Reveals Novel and Conserved Post-Translational Modifications in Sugarcane. Plus One. DOI: 10.1371/journal.pone.0134586

Yilmaz, A., Nishiyama-Jr, M. Y., Garcia-Fuentes, B., Souza, G. M., Janies, D., Gray, J. and Grotewold, E. (2008). GRASSIUS: A Platform for Comparative Regulatory Genomics Across the Grasses. Plant Physiol. 149, 171–180.

Gray, J., Bevan, M., Brutnell, T., Buell, R., Cone, K., Hake, S., Jackson, D., Kellogg, E., Lawrence, C., McCouch, S., Mockler, T., Moose, S., Paterson, A., Peterson, T., Rokshar, D., Souza, G. M., Springer, N., Stein, N., Timmermans, M., Wang, G.-L., Grotewold, E. (2009). Naming Transcription Factors. Plant Physiol. 149, 4-6.

Milton Yutaka Nishiyama-Jr, Fabio Vicente, Paloma Mieko Sato, Savio Siqueira Ferreira, Frank Alex Feltus and Glaucia M Souza. (2011). The Saccharinae transcriptome. In Plant Genetics and Genomics: Crops and Models, Vol. 11: Genetics and Genomics of the Saccharinae. Paterson, Andrew H. (Ed). Springer, New York. ISBN: 978-1-4419-5946-1.

D'Hont, A.; Souza, G.M.; Menossi, M.; Vincentz, M.; Van Sluys M-A ; Glaszmann JC ; Ulian, E. C. (2008). Sugarcane: a Major Source of Sweetness, Alcohol, and Bio-energy. In: Paul Moore; Ray Ming. (Org.). Genomics of Tropical Crop Plants. 

Casu,  R. E., Hotta, C. T., Souza, G. M. Functional Genomics: Transcriptomics of Sugarcane – Current Status and Future Prospects. In: Sugarcane volume of “Genomics of Industrial Crop Plants”. Robert Henry (Org).


Dr. Glaucia Souza holds a degree from the Biosciences Institute of University of São Paulo  (1988), PhD in Biochemistry at the Institute of Chemistry  (1993), post-doctorate in molecular genetics at La Jolla Cancer Research Foundation  (1994) and post-doctorate in molecular genetics at Baylor College of Medicine  (1996).

Post-doctoral position for two years at University of São Paulo, Brazil